How Does AVERSA™ Technology by Nutriband Inc. Improve Safety Profile of Transdermal Drugs Susceptible to Abuse?

## AVERSA™ Technology: Enhancing Safety of Transdermal Drugs

Transdermal drug delivery systems are a promising alternative to traditional oral or injectable medications. These systems deliver drugs directly through the skin, ensuring sustained and consistent drug release. With the growing need for improved drug safety, transdermal technologies have gained significant attention.

Nutriband Inc. has developed AVERSA™, a groundbreaking technology that improves the safety profile of transdermal drugs susceptible to abuse. AVERSA™ incorporates aversive agents into transdermal patches, deterring drug abuse, diversion, and accidental exposure.

AVERSA™ utilizes a combination of bitter or unpleasant-tasting agents and ingredients that produce an unpleasant sensation upon contact with the mucous membranes, such as the mouth or nose. This unpleasant response serves as a strong deterrent against tampering or unauthorized use of the drug.

* Reduced risk of drug abuse and misuse
* Enhanced patient safety
* Improved accessibility to medications for legitimate users
* Decreased liability concerns for healthcare providers

AVERSA™ technology is particularly significant in transdermal fentanyl patches. Fentanyl, a powerful opioid, is often prescribed for severe pain management. However, its high potential for abuse and diversion poses significant safety concerns. AVERSA™-enhanced fentanyl patches can mitigate these risks by effectively deterring abuse.

• Reduces overdose potential: AVERSA™ prevents diversion and tampering, reducing the chances of accidental or intentional overdose.
• Protects children and others: The unpleasant taste and sensation of AVERSA™ discourage children or unauthorized individuals from accessing the drug.
• Enhances patient adherence: By deterring abuse, AVERSA™ promotes proper use of the medication, improving pain management outcomes.

AVERSA™ technology by Nutriband Inc. represents a transformative advancement in transdermal drug safety. By incorporating aversive agents into transdermal patches, AVERSA™ helps prevent the abuse, diversion, misuse, and accidental exposure of drugs with abuse potential. This innovative technology has the potential to improve the lives of millions by enhancing the safety of transdermal drug delivery systems.