Melatonin: A Promising Weapon Against Obesity and Metabolic Disorders
The Obesity Epidemic
Obesity rates have skyrocketed in recent decades, becoming a major health concern worldwide. Characterized by an excess of body fat, obesity increases the risk of severe health complications, including type 2 diabetes, heart disease, and some types of cancer.
Melatonin’s Role Revealed
Studies indicate that melatonin, a natural hormone produced by the body, plays a significant role in regulating metabolism and preventing obesity. Melatonin’s effects on obesity and metabolic function have been extensively researched, with promising results.
Obesity and Visceral Fat Reduction
Research has shown that melatonin supplementation can prevent obesity and reduce visceral fat, the particularly dangerous type that accumulates deep in the abdomen and surrounds vital organs. A study conducted on obese and diabetic rats found that chronic melatonin administration reduced visceral obesity by approximately 3% and ameliorated muscle-fiber atrophy and transformation.
Enhanced Mitochondrial Function
Mitochondria are cellular powerhouses that produce energy for the body. Melatonin has been found to increase mitochondrial activity and content, resulting in a reduction in weight gain. This enhanced mitochondrial function contributes to melatonin’s anti-obesity effects.
Combination Therapy: Melatonin and Cold Water
Intriguingly, the combination of melatonin administration with exposure to slightly cold water (around 17°C) has been shown to enhance weight loss even further. Scientists speculate that this method could provide a valuable strategy for individuals struggling with obesity.
Practical Applications
Professor Ahmad Agil, a leading researcher in this field, suggests incorporating melatonin into daily routines to combat obesity and improve metabolic health:
* Daytime: Exposure to natural light, adequate physical activity, and avoidance of snacks and insulating clothing.
* Nighttime: Sleep in the dark, minimize blue light exposure before bed, and consider fasting to boost endogenous melatonin levels.
Expert Advice
“Our challenge lies in applying melatonin and other strategies, such as intermittent fasting, to address pathologies associated with increased oxidative-mitochondrial stress and metainflammation,” explains Professor Agil. “Melatonin’s potential to delay or stop obesity and its complications warrants further investigation.”
Human Trials and the Future
Promising results from animal studies have paved the way for clinical trials to evaluate melatonin’s effectiveness in humans. Positive findings from these trials could lead to melatonin becoming a valuable therapeutic option for combating obesity and improving overall health.
also read:Melatonin’s Role in Fighting Obesity: New Studies Unveil Promising Findings
Deepika 
Mehek